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NEET
Exam
NEET
Subject
Zoology
Chapter
Locomotion and Movement

NEET · Zoology · Locomotion and Movement

What is the significance of the binding of calcium ions to a...

What is the significance of the binding of calcium ions to a subunit of troponin in muscle contraction?

Options

  1. AIt leads to the binding of myosin to the actin filaments
  2. BIt helps in ATP production
  3. CIt masks the active sites for myosin
  4. DIt causes the release of ADP and Pi from myosin

Correct answer

A. It leads to the binding of myosin to the actin filaments

Step-by-step solution

Muscle contraction is initiated by a signal sent by the central nervous system (CNS) via a motor neuron.The junction between a motor neuron and the sarcolemma of the muscle fibre is called the neuromuscular junction or motor-end plate.When a neural signal reaches the neuromuscular junction, it releases a neurotransmitter (Acetylcholine) which generates an action potential in the sarcolemma. The binding of calcium ions to a subunit of troponin causes the removal of the masking of the active sites for myosin. This allows the myosin head to bind to the exposed active sites on actin, forming a cross bridge and causing contraction of the muscle.

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