Arrange the following events of muscle contraction in the correct chronological order: A. Release of calcium ions into the sarcoplasm. B. Binding of myosin head to the exposed active sites on actin. C. Generation of an action potential in the sarcolemma. D. Binding of calcium with a subunit of troponin on actin filaments. E. Release of a neurotransmitter at the neuromuscular junction. Choose the correct answer from t

Step-by-step solution

Muscle contraction is initiated by a neural signal that reaches the neuromuscular junction, releasing a neurotransmitter like acetylcholine (E). This generates an action potential in the sarcolemma (C). The action potential spreads through the muscle fibre and causes the release of calcium ions into the sarcoplasm from the sarcoplasmic reticulum (A). The increase in calcium levels leads to its binding with a subunit of troponin on actin filaments (D), which removes the masking of active sites for myosin. Finally, u