Which of the following options correctly matches the skeletal or muscular disorder with its primarily affected tissue or location and its underlying chemical or physiological trigger?

Step-by-step solution

Tetany is characterised by rapid spasms (wild contractions) in muscle due to low Ca⁺⁺ in body fluid. Gout is the inflammation of joints due to the accumulation of uric acid crystals, not urea. Osteoporosis is an age-related disorder characterised by decreased bone mass, and a common cause is decreased (not increased) levels of estrogen. Myasthenia gravis is an autoimmune disorder, not a genetic defect, that affects the neuromuscular junction. Answer: Tetany Muscle Low Ca⁺⁺ in body fluid