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NEET2017ZoologyLocomotion and MovementActual

Select the correct combination of statements regarding Myasthenia gravis I. It is an auto immune disorder. II. It causes insufficient acetylcholine binding that effects muscular contraction. III. Antibodies are developed against acetylcholine. IV. Antibodies are developed against acetylcholine receptors. V. It causes drooping of eyelids.

Options

  1. AI, III, IV, VI
  2. BI, III, V, II
  3. CI, II, IV, VI
  4. DII, III, IV, V

Correct answer

C. I, II, IV, VI

Step-by-step solution

Statements I, II, IV and VI are correct. Myasthemia gravis is an auto immune neuromuscular disease that is cogenital. It leads to muscle weakness. It is caused by circulating antibodies that block acetylcholine receptors at the post-synaptic neuromuscular junction inhibiting the excitatory effects of acetylcholine and nicotic receptors at neuromuscular junctions. First noticeable symptom is weakening of eye muscle leading to drooping of eyelids. It is treated medically with acetylcholine esterase inhibitors or immu

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