A married couple seeks medical help for infertility. Clinical evaluation reveals that the female partner has normal, patent fallopian tubes and a normal uterus, but her ovaries fail to produce viable ova. The male partner has a normal sperm count and normal sperm motility. Which of the following Assisted Reproductive Technologies (ART) is the most suitable for this couple?

Step-by-step solution

The female partner cannot produce ova but can provide a suitable environment for fertilization and further embryonic development, as her fallopian tubes and uterus are normal. The male partner has normal sperm parameters. In such cases, the most suitable technique is GIFT (Gamete Intra Fallopian Transfer). An ovum collected from a donor is transferred into the fallopian tube of the female, allowing in-vivo fertilization by the male partner's sperms. ZIFT and ICSI involve in-vitro fertilization, which is unnecessary