What are the two corollaries of the ability of higher vertebrates to differentiate foreign organisms from self-cells?

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This could be because of the protected environment provided early in life.The immune system is designed to recognize and respond to foreign antigens, not to attack self-cells. Higher vertebrates can distinguish foreign molecules as well as foreign organisms, which is the basis for most experimental immunology. Auto-immune disease occurs when the body attacks self-cells, resulting in damage to the body.The primary lymphoid organs in the human body are the bone marrow and thymus, where immature lymphocytes differenti