NEETZoologyHuman Health and Diseases
Enzyme responsible for replication of HIV in macrophages is
Options
- ARNA polymerase
- BDNA ligase
- CDNA polymerase
- DReverse transcriptase
Correct answer
D. Reverse transcriptase
Step-by-step solution
After getting into the body of the person, the virus enters into macrophages where the RNA genome of the virus replicates to form viral DNA with the help of the enzyme reverse transcriptase. This viral DNA gets incorporated into the host cell’s DNA and directs the infected cells to produce virus particles (Figure 8.6). The macrophages continue to produce viruses and in this way acts like a HIV factory. Simultaneously, HIV enters into helper T-lymphocytes , replicates and produces progeny viruses.