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Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): Organs transplanted from any source cannot be simply accepted by the patient's body, and immunosuppressants are often required even after successful tissue matching. Reason (R): The cell-mediated immune response, mediated by T-lymphocytes, is able to differentiate between 'self' and 'non-self' and

Options

  1. ABoth (A) and (R) are true but (R) is not the correct explanation of (A)
  2. B(A) is true but (R) is false
  3. C(A) is false but (R) is true
  4. DBoth (A) and (R) are true and (R) is the correct explanation of (A)

Correct answer

D. Both (A) and (R) are true and (R) is the correct explanation of (A)

Step-by-step solution

Assertion (A) is true. Grafts or organs transplanted from any source cannot be accepted because the body's immune system will reject them. Even after tissue and blood group matching, patients often need to take immunosuppressants for life. Reason (R) is also true and correctly explains the Assertion. The body's immune system is capable of differentiating between 'self' and 'non-self'. The cell-mediated immune response (CMI), which is mediated by T-lymphocytes, is primarily responsible for recognizing the transplant

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