NEETZoologyMicrobes in Human Welfare
A certain bioactive molecule is widely prescribed as a blood cholesterol-lowering agent. Identify the source organism of this molecule and its mechanism of action.
Options
- AYeast (Monascus purpureus); acts by competitively inhibiting the enzyme responsible for synthesis of cholester
- BYeast (Monascus purpureus); acts by allosterically inhibiting the enzyme responsible for synthesis of choleste
- CFungus (Trichoderma polysporum); acts by competitively inhibiting the enzyme responsible for synthesis of chol
- DBacterium (Streptococcus); acts by enzymatically degrading the cholesterol present in the blood vessels.
Correct answer
A. Yeast (Monascus purpureus); acts by competitively inhibiting the enzyme responsible for synthesis of cholester
Step-by-step solution
Statins are bioactive molecules commercialised as blood cholesterol-lowering agents. They are produced by the yeast Monascus purpureus. Statins act by competitively inhibiting the enzyme responsible for the synthesis of cholesterol. Trichoderma polysporum produces Cyclosporin A (an immunosuppressant), while Streptococcus produces Streptokinase (a clot buster). Answer: Yeast (Monascus purpureus); acts by competitively inhibiting the enzyme responsible for synthesis of cholesterol.