IAT IISER2026BiologyChemical Coordination and Integration
Which one of the following correctly describes the mode of action of Follicle Stimulating Hormone (FSH) and estrogen?
Options
- AFSH interacts with membrane-bound receptor and generates cyclic AMP, while estrogen interacts with intracellul
- BBoth FSH and estrogen regulate gene expression via intracellular receptors
- CFSH interacts with intracellular receptor and generates cyclic AMP, while estrogen interacts with membrane-bou
- DBoth FSH and estrogen regulate cellular metabolism via membrane-bound receptors
Correct answer
A. FSH interacts with membrane-bound receptor and generates cyclic AMP, while estrogen interacts with intracellul
Step-by-step solution
FSH is a proteinaceous hormone that cannot pass through the lipid bilayer of the cell membrane. It binds to specific membrane-bound receptors on the target cell surface, leading to the generation of second messengers like cyclic AMP (cAMP), which in turn regulate cellular metabolism. Estrogen is a steroid hormone and is lipid-soluble. It easily diffuses across the cell membrane and binds to intracellular receptors (usually in the nucleus). The hormone-receptor complex then interacts with the genome to regulate gene