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JEE Main202228 Jul 2022Evening ShiftChemistryChemistry in Everyday LifeActual

Two statements in respect of drug-enzyme interaction are given below Statement I : Action of an enzyme can be blocked only when an inhibitor blocks the active site of the enzyme. Statement II : An inhibitor can form a strong covalent bond with the enzyme. In the light of the above statements. Choose the correct answer from the options given below

Options

  1. ABoth Statement I and Statement II are true
  2. BBoth Statement I and Statement II are false
  3. CStatement I is true but Statement II is false
  4. DStatement I is false but Statement II is true

Correct answer

D. Statement I is false but Statement II is true

Step-by-step solution

The first function of an enzyme is to hold the substrate for a chemical reaction. Active sites of enzymes hold the substrate molecule in a suitable position, so that it can be attacked by the reagent effectively. Substrates bind to the active site of the enzyme through a variety of interactions such as ionic bonding, hydrogen bonding, van der Waals interaction or dipole-dipole interaction. Drugs inhibit activities of enzymes. These can block the binding site of the enzyme and prevent the binding of substrate, or ca

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