Fundamentals of Organic ChemistryChemistryAldehydes and Ketones
Which of the following compounds is/are susceptible to oxidative cleavage by periodic acid ( HIO ₄ )?
Options
- AAll of these
Correct answer
1
Step-by-step solution
Periodic acid ( HIO ₄ ) is an oxidizing agent that cleaves carbon-carbon bonds in compounds containing vicinal (adjacent) oxygenated functional groups. Specifically, it is known to cleave: 1. 1,2-diols (vicinal diols) 2. -hydroxy ketones and -hydroxy aldehydes 3. 1,2-diketones Analyzing the given compounds: - The first compound is 4-hydroxyhexan-3-one, which is an -hydroxy ketone. It has a hydroxyl group and a carbonyl group on adjacent carbons, making it susceptible to cleavage by HIO ₄ . - The second compound is