Fundamentals of Organic ChemistryChemistryAldehydes and Ketones
Identify the appropriate reagent required to carry out the following transformation:
Options
- AHOCH ₂ CH ₂ OH
- BCH ₃ CH ₂ OH
- CCH ₃ OH
- DCH ₃ COCH ₃
Correct answer
A. HOCH ₂ CH ₂ OH
Step-by-step solution
The given reaction shows the conversion of a ketone (acetophenone) into a cyclic ketal. The formation of a cyclic ketal with a five-membered ring requires the reaction of the carbonyl compound with a 1,2-diol. Observing the structure of the product, the ketal part consists of a - O - CH ₂- CH ₂- O - group attached to the original carbonyl carbon. This indicates that the reagent used is ethylene glycol, HOCH ₂ CH ₂ OH . The reaction takes place in the presence of a catalytic acid, and water is removed to drive the e