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Fundamentals of Organic ChemistryChemistryAldehydes and Ketones

Identify the appropriate reagent and reaction conditions for the following transformation:

Options

  1. AMethanol, H ⁺
  2. BMethanol, NaOH
  3. CEthanol, NaOH
  4. DEthanol, H ⁺

Correct answer

D. Ethanol, H ⁺

Step-by-step solution

The given transformation involves the conversion of a ketone (acetophenone) into a ketal. The formation of a ketal from a ketone requires an alcohol and an acid catalyst ( H ⁺ ). The reaction does not proceed under basic conditions because a base cannot protonate the hydroxyl group of the hemiketal intermediate to make it a good leaving group (water). Since the final product is a diethyl ketal, which possesses two ethoxy ( -OEt ) groups, the required alcohol is ethanol. Thus, the appropriate reagents and conditions

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