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Fundamentals of Organic ChemistryChemistryBiomolecules

Which of the following reagents can be used to convert into ?

Options

  1. ANaBH ₄
  2. BH ₂ / Pd
  3. CCH ₃ MgBr
  4. DLiAlH ₄

Correct answer

D. LiAlH ₄

Step-by-step solution

The given transformation involves the reduction of a carboxylic acid group ( - COOH ) to a primary alcohol group ( - CH ₂ OH ) while the amino group ( - NH ₂ ) remains unaffected. NaBH ₄ is a mild reducing agent that reduces aldehydes and ketones but cannot reduce carboxylic acids. H ₂/ Pd is used for catalytic hydrogenation of multiple bonds and does not reduce carboxylic acids to alcohols under normal conditions. CH ₃ MgBr is a Grignard reagent which will undergo an acid-base reaction with the acidic proton of th

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