Fundamentals of Organic ChemistryChemistryBiomolecules
Which of the following methods is used to convert an aldose into its next higher homologue?
Options
- AKiliani-Fischer synthesis
- BWohl's method
- CMutarotation
- DAmadori rearrangement
Correct answer
A. Kiliani-Fischer synthesis
Step-by-step solution
The Kiliani-Fischer synthesis is a method used for the chain elongation of carbohydrates. It converts an aldose into its next higher homologue by adding one carbon atom to the carbon chain. Wohl's method is used for chain shortening (degradation) of aldoses. Mutarotation is the change in the specific optical rotation representing the interconversion of and anomers. Amadori rearrangement is an isomerization reaction of N-glycosides of aldoses to 1-amino-1-deoxyketoses. Answer: Kiliani-Fischer synthesis