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Fundamentals of Organic ChemistryChemistryBiomolecules

Which of the following methods is used to convert an aldose into its next higher homologue?

Options

  1. AKiliani-Fischer synthesis
  2. BWohl's method
  3. CMutarotation
  4. DAmadori rearrangement

Correct answer

A. Kiliani-Fischer synthesis

Step-by-step solution

The Kiliani-Fischer synthesis is a method used for the chain elongation of carbohydrates. It converts an aldose into its next higher homologue by adding one carbon atom to the carbon chain. Wohl's method is used for chain shortening (degradation) of aldoses. Mutarotation is the change in the specific optical rotation representing the interconversion of and anomers. Amadori rearrangement is an isomerization reaction of N-glycosides of aldoses to 1-amino-1-deoxyketoses. Answer: Kiliani-Fischer synthesis

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