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Fundamentals of Organic ChemistryChemistryBiomolecules

When one mole of glucose is treated with an excess of periodic acid ( HIO ₄ ), how many moles of HIO ₄ are consumed?

Options

  1. A2
  2. B5
  3. C3
  4. D4

Correct answer

B. 5

Step-by-step solution

Glucose is an aldohexose with an open-chain structure containing one aldehyde group and five hydroxyl groups on adjacent carbon atoms. The structure of glucose is CHO -( CHOH )₄- CH ₂ OH . Periodic acid ( HIO ₄ ) cleaves the carbon-carbon bonds between adjacent carbons bearing hydroxyl groups or a hydroxyl and a carbonyl group. In one molecule of glucose, there are five such carbon-carbon bonds (C1-C2, C2-C3, C3-C4, C4-C5, and C5-C6). Cleavage of each bond consumes one mole of HIO ₄ . Thus, 5 moles of HIO ₄ are con

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