Fundamentals of Organic ChemistryChemistryBiomolecules
When one mole of glucose is treated with an excess of periodic acid ( HIO ₄ ), how many moles of HIO ₄ are consumed?
Options
- A2
- B5
- C3
- D4
Correct answer
B. 5
Step-by-step solution
Glucose is an aldohexose with an open-chain structure containing one aldehyde group and five hydroxyl groups on adjacent carbon atoms. The structure of glucose is CHO -( CHOH )₄- CH ₂ OH . Periodic acid ( HIO ₄ ) cleaves the carbon-carbon bonds between adjacent carbons bearing hydroxyl groups or a hydroxyl and a carbonyl group. In one molecule of glucose, there are five such carbon-carbon bonds (C1-C2, C2-C3, C3-C4, C4-C5, and C5-C6). Cleavage of each bond consumes one mole of HIO ₄ . Thus, 5 moles of HIO ₄ are con