Fundamentals of Organic ChemistryChemistryCarboxylic Acid Derivatives
Identify the major product (A) in the following reaction sequence:
Correct answer
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Step-by-step solution
The given reaction sequence involves two main steps: 1. The first step is the reaction of propanoic acid ( CH ₃ CH ₂ COOH ) with Br ₂ and PBr ₃ . This is the Hell-Volhard-Zelinsky (HVZ) reaction, which selectively brominates the -carbon of the carboxylic acid. The product formed is -bromopropanoic acid. CH ₃ CH ₂ COOH Br ₂/ PBr ₃ CH ₃ CH ( Br ) COOH 2. The second step is the reaction of -bromopropanoic acid with alcoholic ammonia ( NH ₃ ). This is a nucleophilic substitution reaction ( S_N2 ) where the ammonia mole