MHT CET202619 April 2026Evening ShiftChemistryAminesActual
Which from following reactions occurs by removal of -CO- group from amide ?
Options
- AGabriel phthalimide synthesis
- BAmmonolysis of halides
- CMendius reduction
- DHofmann degradation
Correct answer
D. Hofmann degradation
Step-by-step solution
Hofmann bromamide degradation reaction involves the conversion of a primary amide to a primary amine with one carbon atom less than the original amide. The general reaction is given by: R-CO-NH₂ + Br₂ + 4NaOH R-NH₂ + Na₂CO₃ + 2NaBr + 2H₂O In this reaction, the carbonyl group ( -CO- ) is removed from the amide as sodium carbonate. Answer: Hofmann degradation