MHT CET202618 April 2026Morning ShiftChemistryAminesActual
Which from following statements is NOT correct regarding Hofmann's exhaustive alkylation?
Options
- AIn this quaternary ammmonium salts are obtained.
- BTwo moles of alkylhalide when heated with one mole primary amine forms tetraalkyl ammonium halide.
- CDepending on the quantity of alkyl halides treated with primary amine, the mixture of secondary and tertiary a
- DThe reaction is carried out in presence of NaHCO ₃
Correct answer
B. Two moles of alkylhalide when heated with one mole primary amine forms tetraalkyl ammonium halide.
Step-by-step solution
Hofmann's exhaustive alkylation is the process of converting an amine into a quaternary ammonium salt by treating it with an excess of alkyl halide. When a primary amine ( RNH₂ ) is heated with an alkyl halide ( RX ), it undergoes successive nucleophilic substitution reactions: RNH₂ + RX R₂NH + HX (Secondary amine) R₂NH + RX R₃N + HX (Tertiary amine) R₃N + RX R₄N^+X^- (Quaternary ammonium salt) To convert one mole of a primary amine into a tetraalkyl ammonium halide, three moles of alkyl halide are required, not tw