MHT CET202410 May 2024Evening ShiftChemistryAminesActual
Which of the following is Mendius reduction?
Options
- AR - CONH ₂ [ ] Br ₂, KOH _ ( aq ) R - NH ₂
- BR - NH ₂ RX (execess) R ₄ NX
- CR ₄ NX [ ] Moist Ag ₂ O Alkene + R ₃ ~N
- DR - CN [ or LiAlH H ₄] Na / Cl ₂ O OH R - CH ₂ NH ₂⁻
Correct answer
D. R - CN [ or LiAlH H ₄] Na / Cl ₂ O OH R - CH ₂ NH ₂⁻
Step-by-step solution
The correct answer is (4) R - CN Na / CH ₃ OH or LiAlH ₄ R - CH ₂ NH ₂ . This is the reaction for Mendius reduction, which involves the reduction of nitriles ( R CN ) to primary amines ( R - CH ₂ NH ₂ ). The reduction can be carried out using reducing agents like sodium in methanol ( Na / CH ₃ OH ) or lithium aluminum hydride ( LiAlH ₄ ) . Explanation of the other options: - (A) R - CONH ₂+ Br ₂+ KOH ( aq ) R - NH ₂ : This is not Mendius reduction. This is a reaction of an amide ( R - CONH ₂ ) with bromine and alka