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MHT CET202523 Apr 2025Evening ShiftChemistryBiomoleculesActual

What is the total number of -OH groups present in a nucleoside involved in formation of DNA?

Options

  1. A5
  2. B4
  3. C3
  4. D2

Correct answer

D. 2

Step-by-step solution

A nucleoside consists of a nitrogenous base and a pentose sugar. In DNA, the pentose is 2′-deoxyribose, which differs from ribose by the absence of a hydroxyl group at the 2′ position. The hydroxyl groups in 2′-deoxyribose are as follows: the 1′ carbon is bonded to the nitrogenous base and lacks a free -OH , the 2′ carbon has a hydrogen atom ( -H ) instead of -OH , the 3′ carbon has a hydroxyl group, the 4′ carbon is part of the ring structure without a free -OH , and the 5′ carbon has a hydroxyl group. Thus, a 2′-

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