MHT CET202523 Apr 2025Evening ShiftChemistryBiomoleculesActual
What is the total number of -OH groups present in a nucleoside involved in formation of DNA?
Options
- A5
- B4
- C3
- D2
Correct answer
D. 2
Step-by-step solution
A nucleoside consists of a nitrogenous base and a pentose sugar. In DNA, the pentose is 2′-deoxyribose, which differs from ribose by the absence of a hydroxyl group at the 2′ position. The hydroxyl groups in 2′-deoxyribose are as follows: the 1′ carbon is bonded to the nitrogenous base and lacks a free -OH , the 2′ carbon has a hydrogen atom ( -H ) instead of -OH , the 3′ carbon has a hydroxyl group, the 4′ carbon is part of the ring structure without a free -OH , and the 5′ carbon has a hydroxyl group. Thus, a 2′-