The oxyhaemoglobin dissociation curve shifts towards left due to increase in ___________.

Step-by-step solution

The oxyhaemoglobin dissociation curve shifts to the left when the affinity of haemoglobin for oxygen increases. This left shift occurs under conditions such as low pCO₂ , low H^+ concentration (which corresponds to high pH), low temperature, and low 2,3-DPG levels. An increase in pH means a decrease in H^+ concentration, which favours the formation of oxyhaemoglobin and shifts the curve to the left. Conversely, an increase in temperature, pCO₂ , or DPG decreases the affinity of haemoglobin for oxygen and shifts the