Which layer in the Graafian follicle produces the hormone estrogen?

Step-by-step solution

The mature Graafian follicle consists of several cell layers, primarily the theca externa, theca interna, and the membrana granulosa. The production of the hormone estrogen occurs via a coordinated two-cell mechanism. The cells of the theca interna, under the stimulation of luteinizing hormone (LH), synthesize androgens from cholesterol. These androgens then diffuse into the adjacent membrana granulosa. The cells of the membrana granulosa, under the influence of follicle-stimulating hormone (FSH), possess the enzym