Which one of the following is the activator for enzyme hexokinase in glycolysis?

Step-by-step solution

Hexokinase is the first enzyme in the glycolysis pathway, which catalyzes the phosphorylation of glucose to glucose-6-phosphate using ATP. The true substrate for hexokinase is not free ATP, but the Mg ⁺⁺ -ATP complex. The Mg ⁺⁺ ion shields the negative charges of the phosphate groups in ATP, making the terminal phosphorus atom an easier target for nucleophilic attack by the hydroxyl group of glucose. Therefore, Mg ⁺⁺ acts as an essential cofactor and activator for the enzyme hexokinase. Answer: Mg ⁺⁺