When CO_2 concentration in blood increases breathing becomes:

When $\mathrm{CO}_2$ concentration in blood increases breathing becomes faster and deeper. The effect of increased $\mathrm{CO}_2$ is to decrease the affinity of haemoglobin for $\mathrm{O}_2$. Thus, due to Bohr's effect the $\mathrm{CO}_2$ released in respiring tissue accelerates the delivery of oxygen by faster and deeper breathing. Related Theory Bohr and Haldane's effect are two properties of haemoglobin. They help the dissociation of respiratory gases from the haemoglobin molecule based on the physiological conditions of their final destination. Bohr effect is the decrease of the oxygen binding capacity of haemoglobin with the increase of the concentration of carbon dioxide or decrease in $\mathrm{pH}$ whereas Haldane effect is the decrease of the carbon dioxide binding capacity of haemoglobin with the rise in the concentration of oxygen. Furthermore, Bohr effect aids in the release of oxygen from oxyhaemoglobin at the metabolizing tissues while Haldane effect aids in the release of carbon dioxide from carboxyhaemoglobin in the lungs.