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NEET2008ZoologyDigestion and AbsorptionActual

What will happen if the secretion of parietal cells of gastric glands is blocked with an inhibitor?

Options

  1. AGastric juice will be deficient in chymosin
  2. BGastric juice will be deficient in pepsinogen
  3. CIn the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin
  4. DEnterokinase will not be released from the duodenal mucosa and so trypsinogen is not converted to trypsin

Correct answer

C. In the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin

Step-by-step solution

Gastric glands are numerous microscopic tubular glands formed by the epithelium of stomach. The parietal cells (oxyntic cells) are large and most numerous on the side walls of gastric glands. They secrete hydrochloric acid and castle intrinsic factor. The peptic cells (zymogen) cells of gastric glands secrete gastric digestive enzymes as proenzymes-pepsinogen and prorennin and small amount of gastric amylase and gastric lipase. The hydrochloric acid maintains a strongly acidic pH of about 1.5 to 2.5 in the stomach.

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