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NEET2022ZoologyHuman Health and DiseasesActual

Which of the following reasons in mainly responsible for graft rejection in transplantation of organs?

Options

  1. AInability of recipient to differentiate between 'self and 'non-self' tissues/cells
  2. BHumoral immune response only
  3. CAuto-immune response
  4. DCell-mediated response

Correct answer

D. Cell-mediated response

Step-by-step solution

During organ transplantation, the graft rejection takes place due to cell mediated response, in which T-cell controls the identification of Self from Non-self. This rejection can be prevented by Immuno-suppressive agent i.e., Cyclosporin-A.

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