NEET2022ZoologyHuman Health and DiseasesActual
Given below are two statements: Statement I: Autoimmune disorder is a condition where body defense mechanism recognises its own cells as foreign bodies. Statement II: Rheumatoid arthritis is a condition where body does not attack self cells. In the light of the above statements, choose the most appropriate answer from the options given below:
Options
- ABoth statement I and statement II are incorrect
- BStatement I is correct but statement II is incorrect
- CStatement I is incorrect but statement II is correct
- DBoth statement I and statement II are correct
Correct answer
B. Statement I is correct but statement II is incorrect
Step-by-step solution
Autoimmunity, which is an abnormal immune response against self-antigens. The body cells (self) act as antigens and are termed as an autoantigen. The immune system is unable to differentiate between self and non-self tissue in case of auto-immune disorders. The immune system produces antibodies against tissues of the own body or self. For example, in rheumatoid arthritis, a type of immunoglobulin IgM is diagnosed and it is due to autoimmunity of the synovial membrane. These antibodies destroy the synovial membrane,