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NEET2018ZoologyLocomotion and MovementActual

Calcium important in skeletal muscle contraction because

Options

  1. ADetaches the myosin head from the actin filament
  2. BActivates the myosin ATPase by binding to it
  3. CBinds to troponin to remove the masking of active sites on actin for myosin
  4. DPrevents the formation of bonds between the myosin cross bridges and actin filament

Correct answer

C. Binds to troponin to remove the masking of active sites on actin for myosin

Step-by-step solution

Calcium plays a key regulatory role in muscle contraction. Ca 2+ ions bind to troponin and change their shape and position. This, in turn, alters the shape and position of tropomyosin and hence, the active sites on F-actin are exposed. Due to this, myosin cross-bridges are able to bind to these active sites and muscle contraction occurs.

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