NEET2013ZoologyLocomotion and MovementActual
Select the correct statement with respect to disorders of muscles in humans.
Options
- AFailure of neuromuscular transmission in myasthenia gravis can prevent normal swallowing.
- BAccumulation of urea and creatine in the joints causes their inflammation.
- CAn overdose of vitamin D causes osteoporosis.
- DRapid contractions of skeletal muscles cause muscle dystrophy.
Correct answer
A. Failure of neuromuscular transmission in myasthenia gravis can prevent normal swallowing.
Step-by-step solution
Myasthenia gravis is an autoimmune disorder in which autoantibodies bind to cholinergic receptors on muscle cells and impairs the ability of the neurotransmitter acetylcholine to induce muscular contraction. This leads to fatigue, weakening and paralysis of skeletal muscles of mouth and throat which may prevent normal swallowing. Gout arthritis is caused due to excessive formation of uric acid. It gets deposited in synovial joints and causes inflammation. Ostcoporosis is a discase in which bone loses minerals and f