Which statements are True? A. In Hoffmann bromamide degradation, 4 moles of NaOH and 2 moles of Br_2 are consumed per mole of an amide B. Hoffmann bromamide reaction is not given by alkyl amides. C. Primary amines can be synthesized by Hoffmann bromamide degradation. D. Secondary amide on reaction with Br_2 and NaOH will give secondary amine. E. The by-products of Hoffmann degradation are Na_2CO_3, NaBr and H_2O. Choose the correct answer from the options given below:
C. C and E only
The balanced chemical equation for Hoffmann bromamide degradation is: R-CONH _2 + Br _2 + 4 NaOH R-NH _2 + Na _2 CO _3 + 2 NaBr + 2 H _2 O Statement A is false because 1 mole of Br _2 and 4 moles of NaOH are consumed per mole of amide. Statement B is false because primary alkyl amides readily undergo this reaction. Statement C is true as the primary product of this reaction is a primary amine. Statement D is false because the reaction is strictly given by primary amides ( R-CONH _2), not secondary amides. Statement E is true as the by-products formed are Na _2 CO _3, NaBr , and H _2 O . Therefore, only statements C and E are true. Answer: C and E only
Related: Chemistry — Amines · All PYQ Banks