Question
Which from following reactions occurs by removal of -CO- group from amide ?
MHT CET
Chemistry
Amines
2026
MHT CET 2026 (19 April Shift 2)
MHT CET Chemistry Question (2026) — Solution
Options
- A. Gabriel phthalimide synthesis
- B. Ammonolysis of halides
- C. Mendius reduction
- D. Hofmann degradation
Answer
D. Hofmann degradation
Step-by-step solution
Hofmann bromamide degradation reaction involves the conversion of a primary amide to a primary amine with one carbon atom less than the original amide. The general reaction is given by: R-CO-NH_2 + Br_2 + 4NaOH R-NH_2 + Na_2CO_3 + 2NaBr + 2H_2O In this reaction, the carbonyl group (-CO-) is removed from the amide as sodium carbonate. Answer: Hofmann degradation
Related: Chemistry — Amines · All PYQ Banks