Question
The inactive form of Bt toxin is converted to the active form in the insect gut __________.
The inactive form of Bt toxin is converted to the active form in the insect gut __________.
B. due to alkaline pH
Bt toxin is produced by the bacterium Bacillus thuringiensis in an inactive form called protoxin. When an insect ingests this inactive toxin, it enters the gut where the pH is alkaline. The alkaline pH of the insect gut solubilizes the protein crystals, converting the inactive protoxin into its active form. The active toxin then binds to the surface of midgut epithelial cells, creating pores that cause cell swelling and lysis, eventually leading to the death of the insect. Answer: due to alkaline pH
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