Arrange the following events occurring in Renin-Angiotensin mechanism in the correct order : A. Increase in blood pressure and Glomerular filtration rate. B. Reabsorption of Na ^ + and water from distal parts of tubule due to Aldosterone. C. Fall in Glomerular filtration rate. D. Vasoconstriction by Angiotensin II and release of Aldosterone. E. Renin converts Angiotensinogen into Angiotensin I, followed by Angiotensin II. Choose the correct answer from the options given below :
D. C, E, D, B, A
A fall in Glomerular filtration rate (GFR) or glomerular blood pressure activates the juxtaglomerular (JG) cells to release renin. (C) Renin converts angiotensinogen in blood to angiotensin I and further to angiotensin II. (E) Angiotensin II acts as a powerful vasoconstrictor, which increases the glomerular blood pressure. It also activates the adrenal cortex to release Aldosterone. (D) Aldosterone causes the reabsorption of Na ^ + and water from the distal parts of the tubule. (B) This reabsorption and vasoconstriction ultimately lead to an increase in blood pressure and Glomerular filtration rate. (A) The correct sequence of events is C, E, D, B, A. Answer: C, E, D, B, A
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