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NEETBotanyCell - The Unit of Life

A newly synthesized secretory glycoprotein is being processed by a eukaryotic cell. Which of the following represents the correct chronological pathway of the structures it passes through from its inception to its release?

Options

  1. ARough endoplasmic reticulum cis face of Golgi trans face of Golgi Secretory vesicle
  2. BRough endoplasmic reticulum trans face of Golgi cis face of Golgi Secretory vesicle
  3. CSmooth endoplasmic reticulum cis face of Golgi trans face of Golgi Secretory vesicle
  4. DCytoplasm cis face of Golgi trans face of Golgi Rough endoplasmic reticulum

Correct answer

A. Rough endoplasmic reticulum cis face of Golgi trans face of Golgi Secretory vesicle

Step-by-step solution

The protein backbone of a secretory glycoprotein is synthesized by ribosomes attached to the rough endoplasmic reticulum (RER). These proteins are then packaged into vesicles that fuse with the convex cis (forming) face of the Golgi apparatus. Inside the Golgi cisternae, the proteins are modified (glycosylated) into glycoproteins as they move towards the concave trans (maturing) face. Finally, they are packaged into secretory vesicles at the trans face and released for exocytosis. Reversing the cis and trans faces

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