What is required for the reactions catalysed by pyruvic dehydrogenase?

Step-by-step solution

The cytosol, after it enters mitochondrial matrix undergoes oxidative decarboxylation by a complex set of reactions catalyzed by pyruvic dehydrogenase. The reactions catalyzed by pyruvic dehydrogenase require the participation of several coenzymes, including NAD+ and Coenzyme A . During this process, two molecules of NADH are produced from the metabolism of two molecules of pyruvic acid (produced from one glucose molecule during glycolysis). The acetyl CoA then enters a cyclic pathway, tricarboxylic acid cycle, mor