Which component of ATP synthase contains the site for ATP synthesis?

This complex consists of two major components, F1 and F0 (Figure 12.5). The F1 headpiece is a peripheral membrane protein complex and contains the site for synthesis of ATP from ADP and inorganic phosphate. F0 is an integral membrane protein complex that forms the channel through which protons cross the inner membrane. The passage of protons through the channel is coupled to the catalytic site of the F1 component for the production of ATP. For each ATP produced, 4H+ passes through F0 from the intermembrane space to the matrix down the electrochemical proton gradient.