NEETBotanyBiomolecules (B)
Match List-I with List-II regarding the classical example of enzyme inhibition. List-I List-II (A) Malonate (I) Enzyme (B) Succinate (II) Substrate (C) Succinic dehydrogenase (III) Competitive inhibitor (IV) Non-competitive inhibitor Choose the correct answer from the options given below:
Options
- A(A)-(III), (B)-(II), (C)-(I)
- B(A)-(II), (B)-(III), (C)-(I)
- C(A)-(IV), (B)-(II), (C)-(I)
- D(A)-(III), (B)-(I), (C)-(II)
Correct answer
A. (A)-(III), (B)-(II), (C)-(I)
Step-by-step solution
In the classical example of competitive inhibition, malonate acts as the competitive inhibitor. It closely resembles the substrate, which is succinate, in its molecular structure. The enzyme involved in this reaction is succinic dehydrogenase. Malonate competes with succinate for the active site of succinic dehydrogenase. Therefore, the correct match is (A)-(III), (B)-(II), and (C)-(I). Option 2 is incorrect as it swaps the roles of malonate and succinate. Option 3 incorrectly identifies malonate as a non-competiti