Read the following statements carefully: (A) Metal ions form coordination bonds with side chains at the active site and at the same time form one or more coordination bonds with the substrate. (B) Prosthetic groups are distinguished from other cofactors in that they bind transiently to the apoenzyme. (C) Coenzymes are organic compounds whose essential chemical components are often vitamins. (D) The catalytically acti

Step-by-step solution

Statement (A) is correct as metal ions facilitate catalysis by forming coordination bonds with side chains at the active site and with the substrate. Statement (B) is incorrect because prosthetic groups are distinguished by being tightly bound to the apoenzyme, whereas it is coenzymes that bind transiently. Statement (C) is correct as the essential chemical components of many coenzymes are vitamins (e.g., NAD contains the vitamin niacin). Statement (D) is incorrect because the catalytically active enzyme with its b