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Match List-I with List-II regarding cofactors and their properties. List-I List-II (A) Tightly bound organic compound (I) Zinc (B) Transiently binding organic compound (II) Niacin (C) Forms coordination bonds with side chains (III) Haem (D) Essential chemical component of many coenzymes (IV) NAD Choose the correct answer from the options given below:

Options

  1. A(A)-(IV), (B)-(III), (C)-(I), (D)-(II)
  2. B(A)-(III), (B)-(IV), (C)-(II), (D)-(I)
  3. C(A)-(I), (B)-(IV), (C)-(III), (D)-(II)
  4. D(A)-(III), (B)-(IV), (C)-(I), (D)-(II)

Correct answer

D. (A)-(III), (B)-(IV), (C)-(I), (D)-(II)

Step-by-step solution

Prosthetic groups are organic compounds that are tightly bound to the apoenzyme (e.g., Haem). Coenzymes are organic compounds whose association with the apoenzyme is transient (e.g., NAD). Metal ions form coordination bonds with side chains at the active site and with the substrate (e.g., Zinc for carboxypeptidase). The essential chemical components of many coenzymes are vitamins (e.g., Niacin is a vitamin present in the coenzyme NAD). Thus, the correct matching is (A)-(III), (B)-(IV), (C)-(I), (D)-(II). Answer: (A

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