Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): Malonate acts as a competitive inhibitor for the enzyme succinic dehydrogenase. Reason (R): Malonate closely resembles the substrate succinate in its molecular structure, allowing it to compete for the active site. In the light of the above statements, choose the most appropriate answer from the op

Step-by-step solution

Assertion (A) is correct because malonate is a well-known competitive inhibitor of the enzyme succinic dehydrogenase. Reason (R) is also correct and provides the exact mechanism for this inhibition. Competitive inhibitors function by structurally resembling the substrate. Malonate closely resembles the substrate succinate, which allows it to bind to the active site of succinic dehydrogenase, thereby competing with the actual substrate and inhibiting the enzyme's activity. Thus, both Assertion (A) and Reason (R) are