Read the following statements carefully: (A) The protein portion of the enzymes is called the apoenzyme. (B) Prosthetic groups are distinguished from other cofactors in that they are tightly bound to the apoenzyme. (C) Coenzymes serve as co-factors in a number of different enzyme catalysed reactions and bind tightly to the apoenzyme. (D) Catalytic activity is retained when the co-factor is removed from the holoenzyme

Step-by-step solution

Statement (A) is correct: In conjugated enzymes, the protein portion is called the apoenzyme. Statement (B) is correct: Prosthetic groups are organic compounds that are distinguished from other cofactors by their tight binding to the apoenzyme. Statement (C) is incorrect: Coenzymes are organic compounds whose association with the apoenzyme is only transient, usually occurring during the course of catalysis. They do not bind tightly. Statement (D) is incorrect: Catalytic activity is lost when the co-factor is remove