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NEETBotanyBiomolecules (B)

Identify the competitive inhibitor of the enzyme succinic dehydrogenase and the specific substrate it structurally resembles, respectively.

Options

  1. ASuccinate and Malonate
  2. BMalate and Succinate
  3. CMalonate and Oxaloacetate
  4. DMalonate and Succinate

Correct answer

D. Malonate and Succinate

Step-by-step solution

The enzyme succinic dehydrogenase acts on its normal substrate, succinate. Malonate acts as a competitive inhibitor of this enzyme because its molecular structure closely resembles that of succinate. Due to this structural similarity, malonate competes with succinate for the substrate binding site of the enzyme. Thus, the competitive inhibitor is malonate and the substrate it resembles is succinate. Reversing the order or confusing malonate with malate leads to incorrect choices. Answer: Malonate and Succinate

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