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NEETBotanyBiomolecules (B)

Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A) : The inhibition of succinic dehydrogenase by malonate is a classic example of competitive inhibition. Reason (R) : Malonate closely resembles the enzyme succinic dehydrogenase in its molecular structure and competes with the product for the active site. In the light of the above statements, choose

Options

  1. ABoth (A) and (R) are correct and (R) is the correct explanation of (A)
  2. BBoth (A) and (R) are correct but (R) is not the correct explanation of (A)
  3. C(A) is correct but (R) is not correct
  4. DBoth (A) and (R) are not correct

Correct answer

C. (A) is correct but (R) is not correct

Step-by-step solution

Assertion (A) is a correct statement as per NCERT; the inhibition of succinic dehydrogenase by malonate is indeed a well-known example of competitive inhibition. Reason (R) is incorrect because a competitive inhibitor closely resembles the substrate (which is succinate in this case) in its molecular structure, not the enzyme itself. Furthermore, the inhibitor competes with the substrate for the active site of the enzyme, not with the product. Therefore, (A) is correct but (R) is not correct. Answer: (A) is correct

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