Inhibition of Succinic dehydrogenase enzyme by malonate is a classical example of:

Step-by-step solution

Correct answer is option (2) because malonate shows close structural similarity with the substrate and it competes with the substrate for the substrate binding site of the enzyme succinic dehydrogenase. Option (1), (3) and (4) are incorrect as enzyme activation, co-factor inhibition are not showing structural similarity with substrate.