NEET2015BotanyBiomolecules (B)Actual
Which one of the following statements is incorrect?
Options
- AA competitive inhibitor reacts reversibly with the enzyme to form an enzyme-inhibitor complex.
- BIn competitive inhibition, the inhibitor molecule is not chemically changed by the enzyme.
- CThe competitive inhibitor does not affect the rate of breakdown of the enzyme-substrate complex.
- DThe presence of the competitive inhibitor decreases the Km of the enzyme for the substrate.
Correct answer
D. The presence of the competitive inhibitor decreases the Km of the enzyme for the substrate.
Step-by-step solution
Competitive inhibition is a form of enzyme inhibition where binding of the inhibitor to the active site on the enzyme prevents binding of the substrate and vice versa. The presence of a competitive inhibitor increases the Km constant of the enzyme (and not decrease), while it does not affect the Vmax. The competitive inhibitor binds at the active site, so decreases the affinity of the enzyme for its substrate, so Km constant increases. If substrate concentration is increased, inhibition overcomes and attains normal