NEET2008BotanyBiomolecules (B)Actual
A competitive inhibitor of succinic dehydrogenase is
Options
- Amalonate
- Boxaloacetate
- Co-ketoglutarate
- Dmalate
Correct answer
A. malonate
Step-by-step solution
Succinic dehydrogenase oxidised the succinate to fumarate. In eukaryotes succinate dehydrogenase is tightly bound to the inner mitochondrial membrane, in prokaryotes to the plasma membrane. Electrons pass from succinate through the FAD and iron-sulphur centres before entering the chain of electron carriers in the mitochondrial inner membrane Malonate, an analogue of succinate is a strong competitive inhibitor of succinate dehydrogenase and therefore, blocks the activity of citric acid cycle. In Krebs cycle the reve