What is the effect of the degeneration of the thymus gland in old individuals?

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The thymus gland is a lobular structure located between lungs behind sternum on the ventral side of aorta. The thymus plays a major role in the development of the immune system. This gland secretes the peptide hormones called thymosins. Thymosins play a major role in the differentiation of T-lymphocytes, which provide cell-mediated immunity. In addition, thymosins also promote production of antibodies to provide humoral immunity . Thymus is degenerated in old individuals resulting in a decreased production of thymo