NEETZoologyChemical Coordination and Integration
A patient's urine sample tests positive for both glucose and ketone bodies, indicating a severe case of Diabetes mellitus. The appearance of ketone bodies in the urine is primarily the direct result of an abnormally high rate of which of the following metabolic processes?
Options
- ABreakdown of glycogen
- BBreakdown of proteins
- CSynthesis of glucose from non-carbohydrates
- DBreakdown of lipids
Correct answer
D. Breakdown of lipids
Step-by-step solution
In Diabetes mellitus, due to insulin deficiency, cells are unable to adequately take up and utilize blood glucose for energy. To meet energy demands, the body shifts to the breakdown of lipids. This excessive lipid breakdown produces ketone bodies as a byproduct, which accumulate in the blood and are excreted in the urine (ketonuria). Breakdown of glycogen or proteins does not directly produce ketone bodies. Answer: Breakdown of lipids